This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4uvi
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Discovery of pyrimidine isoxazoles InhA in complex with compound 23== | ==Discovery of pyrimidine isoxazoles InhA in complex with compound 23== | ||
| - | <StructureSection load='4uvi' size='340' side='right' caption='[[4uvi]], [[Resolution|resolution]] 1.73Å' scene=''> | + | <StructureSection load='4uvi' size='340' side='right'caption='[[4uvi]], [[Resolution|resolution]] 1.73Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4uvi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UVI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KXU:5-{[(4,6-DIMETHYLPYRIMIDIN-2-YL)SULFANYL]METHYL}-N-[(2-METHYLPYRIDIN-4-YL)METHYL]-1,2-OXAZOLE-3-CARBOXAMIDE'>KXU</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uvi OCA], [https://pdbe.org/4uvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uvi RCSB], [https://www.ebi.ac.uk/pdbsum/4uvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uvi ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: | + | [[Category: Cowan S]] |
| - | [[Category: | + | [[Category: Ghorpade S]] |
| - | [[Category: | + | [[Category: Gingell H]] |
| - | [[Category: | + | [[Category: Madhavapeddi P]] |
| - | [[Category: | + | [[Category: Read JA]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Discovery of pyrimidine isoxazoles InhA in complex with compound 23
| |||||||||||
