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4v04
From Proteopedia
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==FGFR1 in complex with ponatinib.== | ==FGFR1 in complex with ponatinib.== | ||
| - | <StructureSection load='4v04' size='340' side='right' caption='[[4v04]], [[Resolution|resolution]] 2.12Å' scene=''> | + | <StructureSection load='4v04' size='340' side='right'caption='[[4v04]], [[Resolution|resolution]] 2.12Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4v04]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4v04]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V04 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V04 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0LI:3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-{4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}BENZAMIDE'>0LI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.12Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0LI:3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYL-N-{4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)PHENYL}BENZAMIDE'>0LI</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v04 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v04 OCA], [https://pdbe.org/4v04 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v04 RCSB], [https://www.ebi.ac.uk/pdbsum/4v04 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v04 ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/D3DSX2_HUMAN D3DSX2_HUMAN] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Breed | + | [[Category: Large Structures]] |
| - | [[Category: Breeze | + | [[Category: Breed J]] |
| - | [[Category: Klein | + | [[Category: Breeze A]] |
| - | [[Category: Norman | + | [[Category: Klein T]] |
| - | [[Category: Overman | + | [[Category: Norman RA]] |
| - | [[Category: Phillips | + | [[Category: Overman R]] |
| - | [[Category: Tucker | + | [[Category: Phillips C]] |
| - | + | [[Category: Tucker J]] | |
Current revision
FGFR1 in complex with ponatinib.
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Categories: Homo sapiens | Large Structures | Breed J | Breeze A | Klein T | Norman RA | Overman R | Phillips C | Tucker J
