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5a1a

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==2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor==
==2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor==
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<StructureSection load='5a1a' size='340' side='right' caption='[[5a1a]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<SX load='5a1a' size='340' side='right' viewer='molstar' caption='[[5a1a]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5a1a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A1A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5A1A FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5a1a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5A1A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5A1A FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PTQ:2-PHENYLETHYL+1-THIO-BETA-D-GALACTOPYRANOSIDE'>PTQ</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-galactosidase Beta-galactosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.23 3.2.1.23] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PTQ:2-PHENYLETHYL+1-THIO-BETA-D-GALACTOPYRANOSIDE'>PTQ</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5a1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a1a OCA], [http://pdbe.org/5a1a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5a1a RCSB], [http://www.ebi.ac.uk/pdbsum/5a1a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5a1a ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5a1a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5a1a OCA], [https://pdbe.org/5a1a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5a1a RCSB], [https://www.ebi.ac.uk/pdbsum/5a1a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5a1a ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BGAL_ECOLI BGAL_ECOLI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Galactosidase|Galactosidase]]
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*[[Galactosidase 3D structures|Galactosidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Beta-galactosidase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Escherichia coli k-12]]
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[[Category: Large Structures]]
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[[Category: Banerjee, S]]
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[[Category: Banerjee S]]
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[[Category: Bartesaghi, A]]
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[[Category: Bartesaghi A]]
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[[Category: Matthies, D]]
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[[Category: Matthies D]]
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[[Category: Merk, A]]
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[[Category: Merk A]]
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[[Category: Milne, J]]
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[[Category: Milne J]]
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[[Category: Subramaniam, S]]
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[[Category: Subramaniam S]]
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[[Category: Wu, X]]
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[[Category: Wu X]]
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[[Category: Hydrolase]]
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[[Category: Near-atomic]]
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[[Category: Near-atomic resolution cryo-electron microscopy]]
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[[Category: Petg]]
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[[Category: Protein complex]]
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[[Category: Single- particle cryo-em]]
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Current revision

2.2 A resolution cryo-EM structure of beta-galactosidase in complex with a cell-permeant inhibitor

5a1a, resolution 2.20Å

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