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5ajy

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<StructureSection load='5ajy' size='340' side='right'caption='[[5ajy]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
<StructureSection load='5ajy' size='340' side='right'caption='[[5ajy]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ajy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ajy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=87T:N-(4-{[3-(1-METHYL-1H-PYRAZOL-4-YL)-1H-INDOL-5-YL]OXY}PHENYL)GLYCINAMIDE'>87T</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ajv|5ajv]], [[5ajw|5ajw]], [[5ajx|5ajx]], [[5ajz|5ajz]], [[5ak0|5ak0]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=87T:N-(4-{[3-(1-METHYL-1H-PYRAZOL-4-YL)-1H-INDOL-5-YL]OXY}PHENYL)GLYCINAMIDE'>87T</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajy OCA], [http://pdbe.org/5ajy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ajy RCSB], [http://www.ebi.ac.uk/pdbsum/5ajy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajy ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajy OCA], [https://pdbe.org/5ajy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajy RCSB], [https://www.ebi.ac.uk/pdbsum/5ajy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN]] Synthesis and degradation of fructose 2,6-bisphosphate.
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[https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Boyd, S]]
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[[Category: Boyd S]]
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[[Category: Brookfield, J L]]
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[[Category: Brookfield JL]]
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[[Category: Critchlow, S E]]
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[[Category: Critchlow SE]]
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[[Category: Cumming, I A]]
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[[Category: Cumming IA]]
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[[Category: Curtis, N J]]
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[[Category: Curtis NJ]]
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[[Category: Debreczeni, J E]]
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[[Category: Debreczeni JE]]
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[[Category: Degorce, S L]]
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[[Category: Degorce SL]]
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[[Category: Donald, C]]
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[[Category: Donald C]]
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[[Category: Evans, N J]]
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[[Category: Evans NJ]]
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[[Category: Groombridge, S]]
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[[Category: Groombridge S]]
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[[Category: Hopcroft, P]]
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[[Category: Hopcroft P]]
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[[Category: Jones, N P]]
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[[Category: Jones NP]]
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[[Category: Kettle, J G]]
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[[Category: Kettle JG]]
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[[Category: Lamont, S]]
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[[Category: Lamont S]]
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[[Category: Lewis, H J]]
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[[Category: Lewis HJ]]
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[[Category: MacFaull, P]]
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[[Category: MacFaull P]]
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[[Category: McLoughlin, S B]]
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[[Category: McLoughlin SB]]
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[[Category: Rigoreau, L J.M]]
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[[Category: Rigoreau LJM]]
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[[Category: Smith, J M]]
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[[Category: Smith JM]]
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[[Category: St-Gallay, S]]
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[[Category: St-Gallay S]]
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[[Category: Stock, J K]]
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[[Category: Stock JK]]
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[[Category: Wheatley, E R]]
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[[Category: Wheatley ER]]
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[[Category: Wingfield, J]]
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[[Category: Wingfield J]]
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[[Category: Winter, J]]
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[[Category: Winter J]]
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[[Category: Transferase]]
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Current revision

Human PFKFB3 in complex with an indole inhibitor 4

PDB ID 5ajy

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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