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5cu8
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5cu8 is ON HOLD Authors: Bradley, A., Pearce, N., Krojer, T., Ng, J., Talon, R., Vollmar, M., Jose, B., von Delft, F., Bountra, C., Arrowsmith, C.H....) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)== | |
| + | <StructureSection load='5cu8' size='340' side='right'caption='[[5cu8]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5cu8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CU8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CU8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=54T:6-CHLORO-1,3-BENZOTHIAZOL-2-AMINE'>54T</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cu8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cu8 OCA], [https://pdbe.org/5cu8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cu8 RCSB], [https://www.ebi.ac.uk/pdbsum/5cu8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cu8 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI. | ||
| - | + | ==See Also== | |
| - | + | *[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Bradley A]] |
| - | [[Category: | + | [[Category: Edwards A]] |
| - | [[Category: | + | [[Category: Jose B]] |
| - | [[Category: | + | [[Category: Knapp S]] |
| - | [[Category: | + | [[Category: Krojer T]] |
| - | [[Category: | + | [[Category: Ng J]] |
| - | [[Category: | + | [[Category: Pearce N]] |
| - | [[Category: | + | [[Category: Talon R]] |
| - | [[Category: | + | [[Category: Vollmar M]] |
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2-Amino-6-chlorobenzothiazole (SGC - Diamond I04-1 fragment screening)
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bradley A | Edwards A | Jose B | Knapp S | Krojer T | Ng J | Pearce N | Talon R | Vollmar M | Von Delft F
