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1w66
From Proteopedia
(Difference between revisions)
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<StructureSection load='1w66' size='340' side='right'caption='[[1w66]], [[Resolution|resolution]] 1.08Å' scene=''> | <StructureSection load='1w66' size='340' side='right'caption='[[1w66]], [[Resolution|resolution]] 1.08Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1w66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1w66]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W66 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W66 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DKA:DECANOIC+ACID'>DKA</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DKA:DECANOIC+ACID'>DKA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w66 OCA], [https://pdbe.org/1w66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w66 RCSB], [https://www.ebi.ac.uk/pdbsum/1w66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w66 ProSAT], [https://www.topsan.org/Proteins/XMTB/1w66 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w66 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w66 OCA], [https://pdbe.org/1w66 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w66 RCSB], [https://www.ebi.ac.uk/pdbsum/1w66 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w66 ProSAT], [https://www.topsan.org/Proteins/XMTB/1w66 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIPB_MYCTU LIPB_MYCTU] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.[HAMAP-Rule:MF_00013]<ref>PMID:16735476</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Ma | + | [[Category: Ma Q]] |
| - | [[Category: Wilmanns | + | [[Category: Wilmanns M]] |
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Current revision
Structure of a lipoate-protein ligase b from Mycobacterium tuberculosis
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