This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1wh1
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==Solution structure of the fourth PDZ domain of KIAA1095 protein== | ==Solution structure of the fourth PDZ domain of KIAA1095 protein== | ||
| - | <StructureSection load='1wh1' size='340' side='right'caption='[[1wh1 | + | <StructureSection load='1wh1' size='340' side='right'caption='[[1wh1]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wh1]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1wh1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WH1 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wh1 OCA], [https://pdbe.org/1wh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wh1 RCSB], [https://www.ebi.ac.uk/pdbsum/1wh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wh1 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wh1 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PZRN3_HUMAN PZRN3_HUMAN] E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 21: | Line 21: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hayashi | + | [[Category: Hayashi F]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Qin | + | [[Category: Qin X]] |
| - | + | [[Category: Saito K]] | |
| - | [[Category: Saito | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure of the fourth PDZ domain of KIAA1095 protein
| |||||||||||
Categories: Homo sapiens | Large Structures | Hayashi F | Kigawa T | Qin X | Saito K | Yokoyama S
