1wh1

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[[Image:1wh1.jpg|left|200px]]
 
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==Solution structure of the fourth PDZ domain of KIAA1095 protein==
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The line below this paragraph, containing "STRUCTURE_1wh1", creates the "Structure Box" on the page.
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<StructureSection load='1wh1' size='340' side='right'caption='[[1wh1]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wh1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WH1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wh1 OCA], [https://pdbe.org/1wh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wh1 RCSB], [https://www.ebi.ac.uk/pdbsum/1wh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wh1 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wh1 TOPSAN]</span></td></tr>
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{{STRUCTURE_1wh1| PDB=1wh1 | SCENE= }}
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</table>
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== Function ==
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'''Solution structure of the fourth PDZ domain of KIAA1095 protein'''
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[https://www.uniprot.org/uniprot/PZRN3_HUMAN PZRN3_HUMAN] E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1WH1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WH1 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/1wh1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wh1 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi F]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Qin, X.]]
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[[Category: Qin X]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Saito K]]
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[[Category: Saito, K.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Kiaa1095]]
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[[Category: Pdz domain]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 13:39:16 2008''
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Current revision

Solution structure of the fourth PDZ domain of KIAA1095 protein

PDB ID 1wh1

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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