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1whq

From Proteopedia

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[[Image:1whq.png|left|200px]]
 
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{{STRUCTURE_1whq| PDB=1whq | SCENE= }}
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==Solution structure of the N-terminal dsRBD from hypothetical protein BAB28848==
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<StructureSection load='1whq' size='340' side='right'caption='[[1whq]]' scene=''>
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===Solution structure of the N-terminal dsRBD from hypothetical protein BAB28848===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1whq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WHQ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1whq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1whq OCA], [https://pdbe.org/1whq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1whq RCSB], [https://www.ebi.ac.uk/pdbsum/1whq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1whq ProSAT], [https://www.topsan.org/Proteins/RSGI/1whq TOPSAN]</span></td></tr>
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[[1whq]] is a 1 chain structure of [[Helicase]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WHQ OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DHX9_MOUSE DHX9_MOUSE] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/1whq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1whq ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Helicase|Helicase]]
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*[[Helicase 3D structures|Helicase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Muto, Y.]]
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[[Category: Muto Y]]
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[[Category: Nagata, T.]]
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[[Category: Nagata T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M.]]
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[[Category: Terada T]]
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[[Category: Terada, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Double-stranded rna binding domain]]
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[[Category: Dsrbd]]
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[[Category: Dsrm]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rna binding protein]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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Current revision

Solution structure of the N-terminal dsRBD from hypothetical protein BAB28848

PDB ID 1whq

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