This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wim

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:41, 9 May 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1wim.png|left|200px]]
 
-
<!--
+
==Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4==
-
The line below this paragraph, containing "STRUCTURE_1wim", creates the "Structure Box" on the page.
+
<StructureSection load='1wim' size='340' side='right'caption='[[1wim]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1wim]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WIM FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1wim| PDB=1wim | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wim FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wim OCA], [https://pdbe.org/1wim PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wim RCSB], [https://www.ebi.ac.uk/pdbsum/1wim PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wim ProSAT], [https://www.topsan.org/Proteins/RSGI/1wim TOPSAN]</span></td></tr>
-
 
+
</table>
-
===Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/R144A_HUMAN R144A_HUMAN] E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.<ref>PMID:24979766</ref>
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
1WIM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIM OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wim_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wim ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Inoue, M.]]
+
[[Category: Large Structures]]
-
[[Category: Kigawa, T.]]
+
[[Category: Inoue M]]
-
[[Category: Koshiba, S.]]
+
[[Category: Kigawa T]]
-
[[Category: Miyamoto, K.]]
+
[[Category: Koshiba S]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Miyamoto K]]
-
[[Category: Saito, K.]]
+
[[Category: Saito K]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama S]]
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Ring finger domain]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Ubcm4-interacting protein 4]]
+
-
[[Category: Uip4]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 10:03:00 2008''
+

Current revision

Solution Structure of the RING finger Domain of the human UbcM4-interacting Protein 4

PDB ID 1wim

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wim"
Personal tools