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1wjt
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1wjt.png|left|200px]] | ||
| - | + | ==Solution structure of the N-terminal Domain I of mouse transcription elongation factor S-II protein 3== | |
| - | + | <StructureSection load='1wjt' size='340' side='right'caption='[[1wjt]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1wjt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WJT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WJT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | --> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wjt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wjt OCA], [https://pdbe.org/1wjt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wjt RCSB], [https://www.ebi.ac.uk/pdbsum/1wjt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wjt ProSAT], [https://www.topsan.org/Proteins/RSGI/1wjt TOPSAN]</span></td></tr> |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TCEA3_MOUSE TCEA3_MOUSE] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wj/1wjt_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wjt ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Elongation factor 3D structures|Elongation factor 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Inoue M]] | |
| - | [[Category: Inoue | + | [[Category: Kigawa T]] |
| - | [[Category: Kigawa | + | [[Category: Koshiba S]] |
| - | [[Category: Koshiba | + | [[Category: Tochio N]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Tochio | + | [[Category: Yoneyama M]] |
| - | [[Category: Yokoyama | + | |
| - | [[Category: Yoneyama | + | |
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Current revision
Solution structure of the N-terminal Domain I of mouse transcription elongation factor S-II protein 3
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Categories: Large Structures | Mus musculus | Inoue M | Kigawa T | Koshiba S | Tochio N | Yokoyama S | Yoneyama M

