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1xbu

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[[Image:1xbu.gif|left|200px]]
 
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{{Structure
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==Streptomyces griseus aminopeptidase complexed with p-iodo-D-phenylalanine==
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|PDB= 1xbu |SIZE=350|CAPTION= <scene name='initialview01'>1xbu</scene>, resolution 1.20&Aring;
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<StructureSection load='1xbu' size='340' side='right'caption='[[1xbu]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOY:P-IODO-D-PHENYLALANINE'>IOY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[1xbu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XBU FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=IOY:P-IODO-D-PHENYLALANINE'>IOY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbu OCA], [https://pdbe.org/1xbu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xbu RCSB], [https://www.ebi.ac.uk/pdbsum/1xbu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xbu ProSAT]</span></td></tr>
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|RELATEDENTRY=[[1xjo|1XJO]], [[1cp7|1CP7]], [[1qq9|1QQ9]], [[1f2p|1F2P]], [[1f2o|1F2O]], [[1tf8|1TF8]], [[1tf9|1TF9]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xbu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xbu OCA], [http://www.ebi.ac.uk/pdbsum/1xbu PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1xbu RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/APX_STRGG APX_STRGG] An exopeptidase specific for larger hydrophobic amino acids (especially leucine), no cleavage occurs if the next residue is proline (PubMed:8444149).<ref>PMID:2503378</ref> <ref>PMID:8444149</ref> <ref>PMID:8665903</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xb/1xbu_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xbu ConSurf].
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<div style="clear:both"></div>
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'''Streptomyces griseus aminopeptidase complexed with p-iodo-D-phenylalanine'''
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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*[[Streptomyces griseus Aminopeptidase (SGAP)|Streptomyces griseus Aminopeptidase (SGAP)]]
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==About this Structure==
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== References ==
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1XBU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_griseus Streptomyces griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XBU OCA].
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<references/>
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[[Category: Single protein]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces griseus]]
[[Category: Streptomyces griseus]]
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[[Category: Blumberg, S.]]
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[[Category: Blumberg S]]
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[[Category: Gilboa, R.]]
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[[Category: Gilboa R]]
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[[Category: Reiland, V.]]
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[[Category: Reiland V]]
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[[Category: Schomburg, D.]]
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[[Category: Schomburg D]]
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[[Category: Shoham, G.]]
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[[Category: Shoham G]]
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[[Category: Shoham, Y.]]
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[[Category: Shoham Y]]
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[[Category: Spungin-Bialik, A.]]
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[[Category: Spungin-Bialik A]]
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[[Category: calcium activation]]
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[[Category: double-zinc metalloproteinase]]
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[[Category: protein-inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:47:30 2008''
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Current revision

Streptomyces griseus aminopeptidase complexed with p-iodo-D-phenylalanine

PDB ID 1xbu

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