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8jak

From Proteopedia

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m (Protected "8jak" [edit=sysop:move=sysop])
Current revision (05:18, 15 May 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8jak is ON HOLD
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==Human MCC in MCCU state==
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<StructureSection load='8jak' size='340' side='right'caption='[[8jak]], [[Resolution|resolution]] 2.52&Aring;' scene=''>
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Authors: Liu, D.S., Su, J.Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8jak]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JAK FirstGlance]. <br>
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Description: Human MCC in BCCP-BCS state
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.52&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTI:5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL'>BTI</scene></td></tr>
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[[Category: Liu, D.S]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jak OCA], [https://pdbe.org/8jak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jak RCSB], [https://www.ebi.ac.uk/pdbsum/8jak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jak ProSAT]</span></td></tr>
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[[Category: Su, J.Y]]
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] 3-methylcrotonyl-CoA carboxylase deficiency. The disease is caused by variants affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/MCCB_HUMAN MCCB_HUMAN] Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.<ref>PMID:17360195</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Liu DS]]
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[[Category: Su JY]]
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[[Category: Tian XY]]

Current revision

Human MCC in MCCU state

PDB ID 8jak

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