1dz1

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==MOUSE HP1 (M31) C TERMINAL (SHADOW CHROMO) DOMAIN==
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<StructureSection load='1dz1' size='340' side='right' caption='[[1dz1]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''>
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==Mouse HP1 (M31) C terminal (shadow chromo) domain==
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<StructureSection load='1dz1' size='340' side='right'caption='[[1dz1]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1dz1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DZ1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1dz1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DZ1 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ap0|1ap0]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dz1 RCSB], [http://www.ebi.ac.uk/pdbsum/1dz1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dz1 OCA], [https://pdbe.org/1dz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dz1 RCSB], [https://www.ebi.ac.uk/pdbsum/1dz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dz1 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CBX1_MOUSE CBX1_MOUSE] Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/1dz1_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/1dz1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dz1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1dz1" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Ball, L J]]
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[[Category: Ball LJ]]
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[[Category: Brasher, S V]]
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[[Category: Brasher SV]]
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[[Category: Broadhurst, R W]]
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[[Category: Broadhurst RW]]
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[[Category: Fogh, R H]]
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[[Category: Fogh RH]]
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[[Category: Laue, E D]]
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[[Category: Laue ED]]
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[[Category: Murzina, N]]
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[[Category: Murzina N]]
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[[Category: Nielsen, P R]]
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[[Category: Nielsen PR]]
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[[Category: Nietlispach, D]]
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[[Category: Nietlispach D]]
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[[Category: Smith, B O]]
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[[Category: Smith BO]]
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[[Category: Thiru, A]]
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[[Category: Thiru A]]
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[[Category: Chromatin structure]]
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[[Category: Chromo domain]]
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[[Category: Dimeric]]
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[[Category: Heterochromatin protein protein interaction]]
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Current revision

Mouse HP1 (M31) C terminal (shadow chromo) domain

PDB ID 1dz1

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