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2k7n

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==Solution structure of the PPIL1 bound to a fragment of SKIP==
==Solution structure of the PPIL1 bound to a fragment of SKIP==
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<StructureSection load='2k7n' size='340' side='right'caption='[[2k7n]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2k7n' size='340' side='right'caption='[[2k7n]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K7N FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2k7n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K7N FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPIL1, CYPL1, CGI-124, UNQ2425/PRO4984 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k7n OCA], [https://pdbe.org/2k7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k7n RCSB], [https://www.ebi.ac.uk/pdbsum/2k7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k7n ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k7n OCA], [https://pdbe.org/2k7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k7n RCSB], [https://www.ebi.ac.uk/pdbsum/2k7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k7n ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PPIL1_HUMAN PPIL1_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.<ref>PMID:16595688</ref>
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[https://www.uniprot.org/uniprot/PPIL1_HUMAN PPIL1_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.<ref>PMID:16595688</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Shi Y]]
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[[Category: Shi, Y]]
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[[Category: Wang X]]
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[[Category: Wang, X]]
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[[Category: Wu J]]
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[[Category: Wu, J]]
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[[Category: Beta barrel]]
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[[Category: Disorder-order transition]]
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[[Category: Hook-like]]
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[[Category: Isomerase]]
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[[Category: Mrna processing]]
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[[Category: Mrna splicing]]
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[[Category: Rotamase]]
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[[Category: Spliceosome]]
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Current revision

Solution structure of the PPIL1 bound to a fragment of SKIP

PDB ID 2k7n

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