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2kyl
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of MAST2-PDZ complexed with the C-terminus of PTEN== | |
| + | <StructureSection load='2kyl' size='340' side='right'caption='[[2kyl]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2kyl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KYL FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kyl OCA], [https://pdbe.org/2kyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kyl RCSB], [https://www.ebi.ac.uk/pdbsum/2kyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kyl ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MAST2_HUMAN MAST2_HUMAN] Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).[UniProtKB:Q60592] | ||
| - | + | ==See Also== | |
| - | + | *[[Microtubule-associated serine/threonine kinase|Microtubule-associated serine/threonine kinase]] | |
| - | + | *[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cordier F]] | ||
| + | [[Category: Delepierre M]] | ||
| + | [[Category: Lafon M]] | ||
| + | [[Category: Simenel C]] | ||
| + | [[Category: Terrien E]] | ||
| + | [[Category: Wolff N]] | ||
Current revision
Solution structure of MAST2-PDZ complexed with the C-terminus of PTEN
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Categories: Homo sapiens | Large Structures | Cordier F | Delepierre M | Lafon M | Simenel C | Terrien E | Wolff N
