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2lfs

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==Solution structure of the chimeric Af1503 HAMP- EnvZ DHp homodimer; A219F variant==
==Solution structure of the chimeric Af1503 HAMP- EnvZ DHp homodimer; A219F variant==
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<StructureSection load='2lfs' size='340' side='right' caption='[[2lfs]], [[NMR_Ensembles_of_Models | 19 NMR models]]' scene=''>
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<StructureSection load='2lfs' size='340' side='right'caption='[[2lfs]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lfs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"shigella_paradysenteriae"_weldin_1927 "shigella paradysenteriae" weldin 1927]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LFS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lfs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Archaeoglobus_fulgidus_DSM_4304 Archaeoglobus fulgidus DSM 4304] and [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LFS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LFS FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zrx|3zrx]], [[3zrw|3zrw]], [[3zrv|3zrv]], [[2lfr|2lfr]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AF_1503 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=623 "Shigella paradysenteriae" Weldin 1927])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfs OCA], [https://pdbe.org/2lfs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lfs RCSB], [https://www.ebi.ac.uk/pdbsum/2lfs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lfs ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_kinase Histidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.13.3 2.7.13.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lfs OCA], [http://pdbe.org/2lfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lfs RCSB], [http://www.ebi.ac.uk/pdbsum/2lfs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lfs ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ENVZ_SHIFL ENVZ_SHIFL] Member of the two-component regulatory system EnvZ/OmpR involved in the regulation of osmoregulation (genes ompF and ompC). EnvZ functions as a membrane-associated protein kinase that phosphorylates OmpR in response to environmental signals (By similarity). This two-component system plays a role in virulence (By similarity).[UniProtKB:A0A4P7TSF2][UniProtKB:P0AEJ4][https://www.uniprot.org/uniprot/O28769_ARCFU O28769_ARCFU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Shigella paradysenteriae weldin 1927]]
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[[Category: Archaeoglobus fulgidus DSM 4304]]
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[[Category: Histidine kinase]]
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[[Category: Large Structures]]
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[[Category: Coles, M]]
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[[Category: Shigella flexneri]]
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[[Category: Ferris, H U]]
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[[Category: Coles M]]
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[[Category: Hulko, M]]
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[[Category: Ferris HU]]
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[[Category: Lupas, A N]]
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[[Category: Hulko M]]
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[[Category: Martin, J]]
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[[Category: Lupas AN]]
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[[Category: Gearbox model]]
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[[Category: Martin J]]
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[[Category: Hamp domain]]
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[[Category: Transferase]]
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[[Category: Transmembrane signaling]]
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Current revision

Solution structure of the chimeric Af1503 HAMP- EnvZ DHp homodimer; A219F variant

PDB ID 2lfs

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