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2m3e

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==The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2==
==The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2==
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<StructureSection load='2m3e' size='340' side='right' caption='[[2m3e]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2m3e' size='340' side='right'caption='[[2m3e]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m3e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M3E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M3E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m3e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M3E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M3E FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ITGAL, CD11A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m3e OCA], [http://pdbe.org/2m3e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2m3e RCSB], [http://www.ebi.ac.uk/pdbsum/2m3e PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m3e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m3e OCA], [https://pdbe.org/2m3e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m3e RCSB], [https://www.ebi.ac.uk/pdbsum/2m3e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m3e ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN]] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
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[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
==See Also==
==See Also==
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*[[Integrin|Integrin]]
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*[[Integrin 3D structures|Integrin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Diercks, T]]
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[[Category: Large Structures]]
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[[Category: Li, Y]]
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[[Category: Diercks T]]
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[[Category: Millet, O]]
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[[Category: Li Y]]
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[[Category: Surya, W]]
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[[Category: Millet O]]
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[[Category: Torres, J]]
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[[Category: Surya W]]
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[[Category: Integrin alpah l tm domain]]
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[[Category: Torres J]]
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[[Category: Membrane protein]]
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[[Category: Polar interaction]]
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The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2

PDB ID 2m3e

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