This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2mb3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:03, 15 May 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative==
==Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative==
-
<StructureSection load='2mb3' size='340' side='right'caption='[[2mb3]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
+
<StructureSection load='2mb3' size='340' side='right'caption='[[2mb3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2mb3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MB3 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2MB3 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2mb3]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MB3 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L2H:(12S,27S)-12,27-BIS(4-AMINOBUTYL)-4,30-DIMETHYL-3,7,14,18,22,29-HEXAOXA-11,26,31,32,33,34,35,36-OCTAAZAHEPTACYCLO[26.2.1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]HEXATRIACONTA-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-DODECAENE-10,25-DIONE'>L2H</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2mb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mb3 OCA], [http://pdbe.org/2mb3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2mb3 RCSB], [http://www.ebi.ac.uk/pdbsum/2mb3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2mb3 ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L2H:(12S,27S)-12,27-BIS(4-AMINOBUTYL)-4,30-DIMETHYL-3,7,14,18,22,29-HEXAOXA-11,26,31,32,33,34,35,36-OCTAAZAHEPTACYCLO[26.2.1.1~2,5~.1~6,9~.1~13,16~.1~17,20~.1~21,24~]HEXATRIACONTA-1(30),2(36),4,6(35),8,13(34),15,17(33),19,21(32),23,28(31)-DODECAENE-10,25-DIONE'>L2H</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mb3 OCA], [https://pdbe.org/2mb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mb3 RCSB], [https://www.ebi.ac.uk/pdbsum/2mb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mb3 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 21: Line 22:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Chung, W J]]
+
[[Category: Chung WJ]]
-
[[Category: Heddi, B]]
+
[[Category: Heddi B]]
-
[[Category: Iida, K]]
+
[[Category: Iida K]]
-
[[Category: Nagasawa, K]]
+
[[Category: Nagasawa K]]
-
[[Category: Phan, A T]]
+
[[Category: Phan AT]]
-
[[Category: Tera, M]]
+
[[Category: Tera M]]
-
[[Category: Anticancer target]]
+
-
[[Category: Dna-dna inhibitor complex]]
+
-
[[Category: Human telomere]]
+
-
[[Category: Intramolecular g-quadruplex]]
+
-
[[Category: Macrocyclic hexaoxazole]]
+
-
[[Category: Telomestatin derivative]]
+

Current revision

Solution structure of an intramolecular (3+1) human telomeric G-quadruplex bound to a telomestatin derivative

PDB ID 2mb3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools