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1xru

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[[Image:1xru.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of 5-keto-4-deoxyuronate Isomerase from Eschericia coli==
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|PDB= 1xru |SIZE=350|CAPTION= <scene name='initialview01'>1xru</scene>, resolution 1.94&Aring;
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<StructureSection load='1xru' size='340' side='right'caption='[[1xru]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=1PE:PENTAETHYLENE GLYCOL'>1PE</scene>
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<table><tr><td colspan='2'>[[1xru]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XRU FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/4-deoxy-L-threo-5-hexosulose-uronate_ketol-isomerase 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.17 5.3.1.17]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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|GENE= kduI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xru OCA], [https://pdbe.org/1xru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xru RCSB], [https://www.ebi.ac.uk/pdbsum/1xru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xru ProSAT]</span></td></tr>
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</table>
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'''Crystal Structure of 5-keto-4-deoxyuronate Isomerase from Eschericia coli'''
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== Function ==
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[https://www.uniprot.org/uniprot/KDUI_ECOLI KDUI_ECOLI] Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity).[HAMAP-Rule:MF_00687]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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1XRU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XRU OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xr/1xru_consurf.spt"</scriptWhenChecked>
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The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli., Crowther RL, Georgiadis MM, Proteins. 2005 Nov 15;61(3):680-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16152643 16152643]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xru ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Crowther, R L.]]
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[[Category: Crowther RL]]
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[[Category: Georgiadis, M M.]]
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[[Category: Georgiadis MM]]
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[[Category: 1PE]]
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[[Category: ZN]]
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[[Category: beta barrel]]
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[[Category: cupin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:13:44 2008''
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Current revision

Crystal Structure of 5-keto-4-deoxyuronate Isomerase from Eschericia coli

PDB ID 1xru

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