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1yn7
From Proteopedia
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==Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase== | ==Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase== | ||
| - | <StructureSection load='1yn7' size='340' side='right' caption='[[1yn7]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='1yn7' size='340' side='right'caption='[[1yn7]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1yn7]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1yn7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/swine/Iowa/15/1930(H1N1)) Influenza A virus (A/swine/Iowa/15/1930(H1N1))] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YN7 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn7 OCA], [https://pdbe.org/1yn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yn7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn7 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn7_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn7_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yn7 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Beta-2 microglobulin|Beta-2 microglobulin]] | + | *[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]] |
| - | *[[ | + | *[[MHC 3D structures|MHC 3D structures]] |
| + | *[[MHC I 3D structures|MHC I 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Doherty PC]] | |
| - | [[Category: Doherty | + | [[Category: Dunstone MA]] |
| - | [[Category: Dunstone | + | [[Category: Kedzierska K]] |
| - | [[Category: | + | [[Category: Komodromou H]] |
| - | [[Category: | + | [[Category: La Gruta NL]] |
| - | [[Category: | + | [[Category: McCluskey J]] |
| - | [[Category: McCluskey | + | [[Category: Purcell AW]] |
| - | [[Category: Purcell | + | [[Category: Rossjohn J]] |
| - | [[Category: Rossjohn | + | [[Category: Turner SJ]] |
| - | [[Category: Turner | + | [[Category: Walden H]] |
| - | [[Category: Walden | + | [[Category: Webb AI]] |
| - | [[Category: Webb | + | [[Category: Webby R]] |
| - | [[Category: Webby | + | [[Category: Xie W]] |
| - | [[Category: Xie | + | |
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Current revision
Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase
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Categories: Large Structures | Mus musculus | Doherty PC | Dunstone MA | Kedzierska K | Komodromou H | La Gruta NL | McCluskey J | Purcell AW | Rossjohn J | Turner SJ | Walden H | Webb AI | Webby R | Xie W
