This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1yz4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1yz4" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yz4, resolution 2.4&Aring;" /> '''Crystal structure of ...)
Current revision (08:07, 15 May 2024) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1yz4.jpg|left|200px]]<br /><applet load="1yz4" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1yz4, resolution 2.4&Aring;" />
 
-
'''Crystal structure of DUSP15'''<br />
 
-
==About this Structure==
+
==Crystal structure of DUSP15==
-
1YZ4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with BOG and SO4 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YZ4 OCA].
+
<StructureSection load='1yz4' size='340' side='right'caption='[[1yz4]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1yz4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YZ4 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yz4 OCA], [https://pdbe.org/1yz4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yz4 RCSB], [https://www.ebi.ac.uk/pdbsum/1yz4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yz4 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DUS15_HUMAN DUS15_HUMAN]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yz/1yz4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yz4 ConSurf].
 +
<div style="clear:both"></div>
-
==Reference==
+
==See Also==
-
Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase., Yoon TS, Jeong DG, Kim JH, Cho YH, Son JH, Lee JW, Ryu SE, Kim SJ, Proteins. 2005 Nov 15;61(3):694-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16170801 16170801]
+
*[[Dual specificity phosphatase 3D structures|Dual specificity phosphatase 3D structures]]
 +
*[[MAP kinase phosphatase|MAP kinase phosphatase]]
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Protein-tyrosine-phosphatase]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Cho YH]]
-
[[Category: Cho, Y.H.]]
+
[[Category: Jeong DG]]
-
[[Category: Jeong, D.G.]]
+
[[Category: Jeong SK]]
-
[[Category: Jeong, S.K.]]
+
[[Category: Kim JH]]
-
[[Category: Kim, J.H.]]
+
[[Category: Kim SJ]]
-
[[Category: Kim, S.J.]]
+
[[Category: Lee JW]]
-
[[Category: Lee, J.W.]]
+
[[Category: Ryu SE]]
-
[[Category: Ryu, S.E.]]
+
[[Category: Son JH]]
-
[[Category: Son, J.H.]]
+
[[Category: Yoon TS]]
-
[[Category: Yoon, T.S.]]
+
-
[[Category: BOG]]
+
-
[[Category: SO4]]
+
-
[[Category: hydrolase]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 07:08:55 2007''
+

Current revision

Crystal structure of DUSP15

PDB ID 1yz4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools