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1z23
From Proteopedia
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==The serine-rich domain from Crk-associated substrate (p130Cas)== | ==The serine-rich domain from Crk-associated substrate (p130Cas)== | ||
| - | <StructureSection load='1z23' size='340' side='right' caption='[[1z23 | + | <StructureSection load='1z23' size='340' side='right'caption='[[1z23]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1z23]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1z23]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z23 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z23 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z23 OCA], [https://pdbe.org/1z23 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z23 RCSB], [https://www.ebi.ac.uk/pdbsum/1z23 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z23 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/BCAR1_RAT BCAR1_RAT] Appears to have a central function in transformation of some cell types. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BCAR1_RAT BCAR1_RAT] Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. Implicated in induction of cell migration (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z23_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z23_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z23 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1z23" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Briknarova | + | [[Category: Briknarova K]] |
| - | [[Category: Eggleston | + | [[Category: Eggleston E]] |
| - | [[Category: Ely | + | [[Category: Ely KR]] |
| - | [[Category: Havert | + | [[Category: Havert ML]] |
| - | [[Category: Hoyt | + | [[Category: Hoyt DW]] |
| - | [[Category: Li | + | [[Category: Li C]] |
| - | [[Category: Nasertorabi | + | [[Category: Nasertorabi F]] |
| - | [[Category: Olson | + | [[Category: Olson AJ]] |
| - | [[Category: Vuori | + | [[Category: Vuori K]] |
| - | + | ||
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Current revision
The serine-rich domain from Crk-associated substrate (p130Cas)
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Categories: Large Structures | Rattus norvegicus | Briknarova K | Eggleston E | Ely KR | Havert ML | Hoyt DW | Li C | Nasertorabi F | Olson AJ | Vuori K

