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1z2z

From Proteopedia

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[[Image:1z2z.gif|left|200px]]
 
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{{Structure
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==Crystal Structure of the Putative tRNA pseudouridine synthase D (TruD) from Methanosarcina mazei, Northeast Structural Genomics Target MaR1==
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|PDB= 1z2z |SIZE=350|CAPTION= <scene name='initialview01'>1z2z</scene>, resolution 2.60&Aring;
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<StructureSection load='1z2z' size='340' side='right'caption='[[1z2z]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[1z2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z2Z FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Pseudouridylate_synthase Pseudouridylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.70 4.2.1.70] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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|GENE= truD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2209 Methanosarcina mazei])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG0585 COG0585], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02577 PSTD1]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2z OCA], [https://pdbe.org/1z2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z2z RCSB], [https://www.ebi.ac.uk/pdbsum/1z2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z2z ProSAT], [https://www.topsan.org/Proteins/NESGC/1z2z TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z2z OCA], [http://www.ebi.ac.uk/pdbsum/1z2z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1z2z RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/TRUD_METMA TRUD_METMA] Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/1z2z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z2z ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of the Putative tRNA pseudouridine synthase D (TruD) from Methanosarcina mazei, Northeast Structural Genomics Target MaR1'''
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==See Also==
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*[[Pseudouridine synthase 3D structures|Pseudouridine synthase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1Z2Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanosarcina_mazei Methanosarcina mazei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z2Z OCA].
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[[Category: Large Structures]]
[[Category: Methanosarcina mazei]]
[[Category: Methanosarcina mazei]]
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[[Category: Pseudouridylate synthase]]
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[[Category: Acton TB]]
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[[Category: Single protein]]
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[[Category: Ciano M]]
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[[Category: Acton, T B.]]
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[[Category: Forouhar F]]
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[[Category: Ciano, M.]]
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[[Category: Hunt JF]]
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[[Category: Forouhar, F.]]
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[[Category: Montelione GT]]
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[[Category: Hunt, J F.]]
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[[Category: Tong L]]
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[[Category: Montelione, G T.]]
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[[Category: Yong W]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Tong, L.]]
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[[Category: Yong, W.]]
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[[Category: alpha-beta protein.]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:28:18 2008''
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Current revision

Crystal Structure of the Putative tRNA pseudouridine synthase D (TruD) from Methanosarcina mazei, Northeast Structural Genomics Target MaR1

PDB ID 1z2z

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