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1z52
From Proteopedia
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<StructureSection load='1z52' size='340' side='right'caption='[[1z52]], [[Resolution|resolution]] 2.38Å' scene=''> | <StructureSection load='1z52' size='340' side='right'caption='[[1z52]], [[Resolution|resolution]] 2.38Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1z52]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1z52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeromonas_hydrophila Aeromonas hydrophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z52 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z52 OCA], [https://pdbe.org/1z52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z52 RCSB], [https://www.ebi.ac.uk/pdbsum/1z52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z52 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/AERA_AERHY AERA_AERHY] Aerolysin is a cytolytic toxin exported by the Gram negative Aeromonas bacteria. The mature toxin binds to eukaryotic cells and aggregates to form holes approximately 3 nm in diameter, leading to destruction of the membrane permeability barrier and osmotic lysis. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Aeromonas | + | [[Category: Aeromonas hydrophila]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Feil | + | [[Category: Feil SC]] |
| - | [[Category: Parker | + | [[Category: Parker MW]] |
| - | [[Category: Tang | + | [[Category: Tang JW]] |
| - | + | ||
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Current revision
Proaerolysin Mutant W373L
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