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1zad

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==Structure of cytotoxin I (CTI) from Naja Oxiana in complex with DPC micelle==
==Structure of cytotoxin I (CTI) from Naja Oxiana in complex with DPC micelle==
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<StructureSection load='1zad' size='340' side='right' caption='[[1zad]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1zad' size='340' side='right'caption='[[1zad]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1zad]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZAD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZAD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1zad]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZAD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZAD FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rl5|1rl5]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zad OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1zad RCSB], [http://www.ebi.ac.uk/pdbsum/1zad PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zad FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zad OCA], [https://pdbe.org/1zad PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zad RCSB], [https://www.ebi.ac.uk/pdbsum/1zad PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zad ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/3SA1_NAJOX 3SA1_NAJOX] This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops. Cytotoxins which have a 'Pro-30' (P-type) interacts with membrane stronger that those which have a Ser-28 (S-type). CTI interacts with membrane weaker than CTII.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/1zad_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/za/1zad_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zad ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1zad" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Naja oxiana]]
[[Category: Naja oxiana]]
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[[Category: Arseniev, A S.]]
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[[Category: Arseniev AS]]
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[[Category: Dubinnyi, M A.]]
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[[Category: Dubinnyi MA]]
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[[Category: Dubovskii, P V.]]
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[[Category: Dubovskii PV]]
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[[Category: Efremov, R G.]]
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[[Category: Efremov RG]]
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[[Category: Konshina, A G.]]
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[[Category: Konshina AG]]
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[[Category: Pustovalova, Y E.]]
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[[Category: Pustovalova YE]]
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[[Category: Utkin, Y N.]]
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[[Category: Utkin YN]]
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[[Category: Antiparallel beta-sheet]]
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[[Category: Beta-turn type i]]
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[[Category: Beta-turn type ii]]
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[[Category: Toxin]]
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Current revision

Structure of cytotoxin I (CTI) from Naja Oxiana in complex with DPC micelle

PDB ID 1zad

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