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1zkh

From Proteopedia

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{{Seed}}
 
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[[Image:1zkh.png|left|200px]]
 
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<!--
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==Solution structure of a human ubiquitin-like domain in SF3A1==
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The line below this paragraph, containing "STRUCTURE_1zkh", creates the "Structure Box" on the page.
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<StructureSection load='1zkh' size='340' side='right'caption='[[1zkh]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1zkh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZKH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zkh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zkh OCA], [https://pdbe.org/1zkh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zkh RCSB], [https://www.ebi.ac.uk/pdbsum/1zkh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zkh ProSAT]</span></td></tr>
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{{STRUCTURE_1zkh| PDB=1zkh | SCENE= }}
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</table>
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== Function ==
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===Solution structure of a human ubiquitin-like domain in SF3A1===
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[https://www.uniprot.org/uniprot/SF3A1_HUMAN SF3A1_HUMAN] Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1ZKH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZKH OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zk/1zkh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zkh ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Avvakumov, G V.]]
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[[Category: Arrowsmith CH]]
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[[Category: Dhe-Paganon, S.]]
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[[Category: Avvakumov GV]]
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[[Category: Edwards, A.]]
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[[Category: Dhe-Paganon S]]
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[[Category: Guido, V.]]
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[[Category: Edwards A]]
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[[Category: Lemak, A.]]
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[[Category: Guido V]]
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[[Category: Lukin, J A.]]
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[[Category: Lemak A]]
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[[Category: Mackenzie, F.]]
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[[Category: Lukin JA]]
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[[Category: Newman, E M.]]
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[[Category: Mackenzie F]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Newman EM]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom M]]
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[[Category: Xue, S.]]
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[[Category: Xue S]]
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[[Category: Sgc]]
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[[Category: Splicing factor]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Ubiquitin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:45:49 2009''
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Current revision

Solution structure of a human ubiquitin-like domain in SF3A1

PDB ID 1zkh

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