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2a8i

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Current revision (08:16, 15 May 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2a8i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A8I FirstGlance]. <br>
<table><tr><td colspan='2'>[[2a8i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A8I FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a8i OCA], [https://pdbe.org/2a8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a8i RCSB], [https://www.ebi.ac.uk/pdbsum/2a8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a8i ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a8i OCA], [https://pdbe.org/2a8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a8i RCSB], [https://www.ebi.ac.uk/pdbsum/2a8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a8i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TASP1_HUMAN TASP1_HUMAN]] Protease involved in MLL processing and, consequently, in the correct expression of the early HOXA gene cluster.
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[https://www.uniprot.org/uniprot/TASP1_HUMAN TASP1_HUMAN] Protease involved in MLL processing and, consequently, in the correct expression of the early HOXA gene cluster.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dunn, B M]]
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[[Category: Dunn BM]]
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[[Category: Khan, J A]]
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[[Category: Khan JA]]
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[[Category: Tong, L]]
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[[Category: Tong L]]
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[[Category: Asparaginase]]
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[[Category: Glycosylspaginse]]
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[[Category: Hydrolase]]
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[[Category: Mll]]
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[[Category: Taspase1]]
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[[Category: Threonine aspartase]]
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Current revision

Crystal Structure of human Taspase1

PDB ID 2a8i

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