2ae8

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[[Image:2ae8.gif|left|200px]]<br /><applet load="2ae8" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2ae8, resolution 2.01&Aring;" />
 
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'''Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315'''<br />
 
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==About this Structure==
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==Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315==
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2AE8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Imidazoleglycerol-phosphate_dehydratase Imidazoleglycerol-phosphate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.19 4.2.1.19] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AE8 OCA].
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<StructureSection load='2ae8' size='340' side='right'caption='[[2ae8]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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[[Category: Imidazoleglycerol-phosphate dehydratase]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2ae8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AE8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AE8 FirstGlance]. <br>
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[[Category: Staphylococcus aureus]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
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[[Category: Collart, F.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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[[Category: Holzle, D.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ae8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ae8 OCA], [https://pdbe.org/2ae8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ae8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ae8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ae8 ProSAT], [https://www.topsan.org/Proteins/MCSG/2ae8 TOPSAN]</span></td></tr>
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[[Category: Joachimiak, A.]]
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</table>
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[[Category: Kim, Y.]]
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== Function ==
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[https://www.uniprot.org/uniprot/HIS7_STAAN HIS7_STAAN]
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[[Category: Quartey, P.]]
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== Evolutionary Conservation ==
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[[Category: MG]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: beta-alpha-beta sandwich]]
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Check<jmol>
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[[Category: duplication of a half-domain]]
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<jmolCheckbox>
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[[Category: imidazoleglycerol-phosphate dehydratase (igpd)]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ae/2ae8_consurf.spt"</scriptWhenChecked>
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[[Category: mcsg]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: midwest center for structural genomics]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: protein structure initiative]]
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</jmolCheckbox>
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[[Category: psi]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ae8 ConSurf].
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[[Category: structural genomics]]
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<div style="clear:both"></div>
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__TOC__
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:26:29 2008''
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Staphylococcus aureus subsp. aureus N315]]
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[[Category: Collart F]]
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[[Category: Holzle D]]
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[[Category: Joachimiak A]]
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[[Category: Kim Y]]
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[[Category: Quartey P]]

Current revision

Crystal Structure of Imidazoleglycerol-phosphate Dehydratase from Staphylococcus aureus subsp. aureus N315

PDB ID 2ae8

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