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2afj
From Proteopedia
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==SPRY domain-containing SOCS box protein 2 (SSB-2)== | ==SPRY domain-containing SOCS box protein 2 (SSB-2)== | ||
| - | <StructureSection load='2afj' size='340' side='right' caption='[[2afj | + | <StructureSection load='2afj' size='340' side='right'caption='[[2afj]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2afj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2afj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AFJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2afj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afj OCA], [https://pdbe.org/2afj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2afj RCSB], [https://www.ebi.ac.uk/pdbsum/2afj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2afj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/SPSB2_MOUSE SPSB2_MOUSE] Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afj_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/af/2afj_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2afj ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2afj" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Babon | + | [[Category: Babon JJ]] |
| - | [[Category: Masters | + | [[Category: Masters SL]] |
| - | [[Category: Nicholson | + | [[Category: Nicholson SE]] |
| - | [[Category: Nicola | + | [[Category: Nicola NA]] |
| - | [[Category: Norton | + | [[Category: Norton RS]] |
| - | [[Category: Palmer | + | [[Category: Palmer KR]] |
| - | [[Category: Smith | + | [[Category: Smith BJ]] |
| - | [[Category: Willson | + | [[Category: Willson TA]] |
| - | [[Category: Yao | + | [[Category: Yao S]] |
| - | [[Category: Zhang | + | [[Category: Zhang JG]] |
| - | + | ||
| - | + | ||
Current revision
SPRY domain-containing SOCS box protein 2 (SSB-2)
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Categories: Large Structures | Mus musculus | Babon JJ | Masters SL | Nicholson SE | Nicola NA | Norton RS | Palmer KR | Smith BJ | Willson TA | Yao S | Zhang JG
