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2ahr

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Current revision (08:17, 15 May 2024) (edit) (undo)
 
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<StructureSection load='2ahr' size='340' side='right'caption='[[2ahr]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='2ahr' size='340' side='right'caption='[[2ahr]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ahr]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_(serotype_1_/_m1_gas) Streptococcus pyogenes (serotype 1 / m1 gas)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AHR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ahr]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pyogenes_M1_GAS Streptococcus pyogenes M1 GAS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AHR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1yqg|1yqg]], [[2ag8|2ag8]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyrroline-5-carboxylate_reductase Pyrroline-5-carboxylate reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.2 1.5.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ahr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahr OCA], [https://pdbe.org/2ahr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ahr RCSB], [https://www.ebi.ac.uk/pdbsum/2ahr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ahr ProSAT], [https://www.topsan.org/Proteins/MCSG/2ahr TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ahr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ahr OCA], [https://pdbe.org/2ahr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ahr RCSB], [https://www.ebi.ac.uk/pdbsum/2ahr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ahr ProSAT], [https://www.topsan.org/Proteins/MCSG/2ahr TOPSAN]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9A1S9_STRP1 Q9A1S9_STRP1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyrroline-5-carboxylate reductase]]
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[[Category: Streptococcus pyogenes M1 GAS]]
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[[Category: Holzle, D]]
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[[Category: Holzle D]]
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[[Category: Joachimiak, A]]
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[[Category: Joachimiak A]]
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[[Category: Lezondra, L]]
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[[Category: Lezondra L]]
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[[Category: Structural genomic]]
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[[Category: Nocek B]]
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[[Category: Nocek, B]]
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[[Category: 1-pyrroline-5-carboxylate reductase]]
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[[Category: Doain swapping]]
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[[Category: Human pathogen]]
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[[Category: Mcsg]]
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[[Category: Oxidoreductase]]
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[[Category: Proline biosynthesis]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Pyrroline reductase]]
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[[Category: Rossmann fold]]
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[[Category: Streptococcus pyogene]]
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Current revision

Crystal Structures of 1-Pyrroline-5-Carboxylate Reductase from Human Pathogen Streptococcus pyogenes

PDB ID 2ahr

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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