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1br0

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==THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A==
==THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A==
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<StructureSection load='1br0' size='340' side='right' caption='[[1br0]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
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<StructureSection load='1br0' size='340' side='right'caption='[[1br0]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1br0]] is a 1 chain structure. The November 2013 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''SNARE Proteins'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2013_11 10.2210/rcsb_pdb/mom_2013_11]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BR0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BR0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1br0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. The November 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''SNARE Proteins'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_11 10.2210/rcsb_pdb/mom_2013_11]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BR0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BR0 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1br0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1br0 OCA], [http://pdbe.org/1br0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1br0 RCSB], [http://www.ebi.ac.uk/pdbsum/1br0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1br0 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1br0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1br0 OCA], [https://pdbe.org/1br0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1br0 RCSB], [https://www.ebi.ac.uk/pdbsum/1br0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1br0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STX1A_RAT STX1A_RAT]] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
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[https://www.uniprot.org/uniprot/STX1A_RAT STX1A_RAT] Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1br0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1br0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</div>
</div>
<div class="pdbe-citations 1br0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1br0" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Syntaxin 3D structures|Syntaxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Rattus norvegicus]]
[[Category: SNARE Proteins]]
[[Category: SNARE Proteins]]
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[[Category: Dubulova, I]]
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[[Category: Dubulova I]]
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[[Category: Fernandez, I]]
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[[Category: Fernandez I]]
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[[Category: Rizo, J]]
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[[Category: Rizo J]]
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[[Category: Sudhof, T C]]
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[[Category: Sudhof TC]]
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[[Category: Ubach, J]]
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[[Category: Ubach J]]
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[[Category: Zhang, X]]
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[[Category: Zhang X]]
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[[Category: Membrane fusion]]
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[[Category: Membrane protein]]
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[[Category: Synaptic vesicle exocytosis]]
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[[Category: Syntaxin]]
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Current revision

THREE DIMENSIONAL STRUCTURE OF THE N-TERMINAL DOMAIN OF SYNTAXIN 1A

PDB ID 1br0

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