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1eo1

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{{Seed}}
 
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[[Image:1eo1.png|left|200px]]
 
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==Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum==
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The line below this paragraph, containing "STRUCTURE_1eo1", creates the "Structure Box" on the page.
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<StructureSection load='1eo1' size='340' side='right'caption='[[1eo1]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1eo1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EO1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EO1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eo1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eo1 OCA], [https://pdbe.org/1eo1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eo1 RCSB], [https://www.ebi.ac.uk/pdbsum/1eo1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eo1 ProSAT], [https://www.topsan.org/Proteins/NESGC/1eo1 TOPSAN]</span></td></tr>
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{{STRUCTURE_1eo1| PDB=1eo1 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/O27243_METTH O27243_METTH]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eo/1eo1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eo1 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The solution structure of MTH1175, a 124-residue protein from the archaeon Methanobacterium thermoautotrophicum has been determined by NMR spectroscopy. MTH1175 is part of a family of conserved hypothetical proteins (COG1433) with unknown functions which contains multiple paralogs from all complete archaeal genomes and the archaeal gene-rich bacterium Thermotoga maritima. Sequence similarity indicates this protein family may be related to the nitrogen fixation proteins NifB and NifX. MTH1175 adopts an alpha/beta topology with a single mixed beta-sheet, and contains two flexible loops and an unstructured C-terminal tail. The fold resembles that of Ribonuclease H and similar proteins, but differs from these in several respects, and is not likely to have a nuclease activity.
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===Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum===
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NMR structure determination and structure-based functional characterization of conserved hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum.,Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA J Struct Funct Genomics. 2000;1(1):15-25. PMID:12836677<ref>PMID:12836677</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_12836677}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1eo1" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 12836677 is the PubMed ID number.
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== References ==
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-->
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<references/>
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{{ABSTRACT_PUBMED_12836677}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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1EO1 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EO1 OCA].
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==Reference==
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NMR structure determination and structure-based functional characterization of conserved hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum., Cort JR, Yee A, Edwards AM, Arrowsmith CH, Kennedy MA, J Struct Funct Genomics. 2000;1(1):15-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12836677 12836677]
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[[Category: Methanothermobacter thermautotrophicus]]
[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Cort, J R.]]
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[[Category: Cort JR]]
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[[Category: Kennedy, M A.]]
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[[Category: Kennedy MA]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Mixed a/b protein]]
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[[Category: Mixed beta sheet]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Strand order 321456]]
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[[Category: Strands 2 and 6 antiparallel to rest.]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 12:06:21 2008''
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Current revision

Solution structure of hypothetical protein MTH1175 from Methanobacterium thermoautotrophicum

PDB ID 1eo1

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