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1hdd

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<StructureSection load='1hdd' size='340' side='right'caption='[[1hdd]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1hdd' size='340' side='right'caption='[[1hdd]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hdd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HDD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1HDD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hdd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HDD FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1hdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hdd OCA], [http://pdbe.org/1hdd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hdd RCSB], [http://www.ebi.ac.uk/pdbsum/1hdd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hdd ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hdd OCA], [https://pdbe.org/1hdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hdd RCSB], [https://www.ebi.ac.uk/pdbsum/1hdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hdd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME]] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
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[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kissinger, C R]]
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[[Category: Synthetic construct]]
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[[Category: Kornberg, T B]]
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[[Category: Kissinger CR]]
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[[Category: Liu, B]]
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[[Category: Kornberg TB]]
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[[Category: Martin-Blanco, E]]
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[[Category: Liu B]]
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[[Category: Pabo, C O]]
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[[Category: Martin-Blanco E]]
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[[Category: Double helix]]
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[[Category: Pabo CO]]
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[[Category: Protein-dna complex]]
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[[Category: Transcription-dna complex]]
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Current revision

CRYSTAL STRUCTURE OF AN ENGRAILED HOMEODOMAIN-DNA COMPLEX AT 2.8 ANGSTROMS RESOLUTION: A FRAMEWORK FOR UNDERSTANDING HOMEODOMAIN-DNA INTERACTIONS

PDB ID 1hdd

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