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1mpe

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==Ensemble of 20 structures of the tetrameric mutant of the B1 domain of streptococcal protein G==
==Ensemble of 20 structures of the tetrameric mutant of the B1 domain of streptococcal protein G==
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<StructureSection load='1mpe' size='340' side='right' caption='[[1mpe]], [[NMR_Ensembles_of_Models | 21 NMR models]]' scene=''>
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<StructureSection load='1mpe' size='340' side='right'caption='[[1mpe]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1mpe]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_sp._'group_g' Streptococcus sp. 'group g']. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MPE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MPE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1mpe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_sp._'group_G' Streptococcus sp. 'group G']. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MPE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MPE FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gb1|1gb1]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1320 Streptococcus sp. 'group G'])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mpe OCA], [https://pdbe.org/1mpe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mpe RCSB], [https://www.ebi.ac.uk/pdbsum/1mpe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mpe ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mpe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mpe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1mpe RCSB], [http://www.ebi.ac.uk/pdbsum/1mpe PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG]] Binds to the constant Fc region of IgG with high affinity.
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[https://www.uniprot.org/uniprot/SPG1_STRSG SPG1_STRSG] Binds to the constant Fc region of IgG with high affinity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mp/1mpe_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mp/1mpe_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mpe ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1mpe" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptococcus sp. 'group g']]
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[[Category: Large Structures]]
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[[Category: Dobrodumov, A]]
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[[Category: Streptococcus sp. 'group G']]
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[[Category: Dyda, F]]
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[[Category: Dobrodumov A]]
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[[Category: Frank, M K]]
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[[Category: Dyda F]]
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[[Category: Gronenborn, A M]]
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[[Category: Frank MK]]
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[[Category: Channel]]
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[[Category: Gronenborn AM]]
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[[Category: Protein binding]]
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[[Category: Strand-exchanged tetramer]]
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Current revision

Ensemble of 20 structures of the tetrameric mutant of the B1 domain of streptococcal protein G

PDB ID 1mpe

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