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1nyp

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==4th LIM domain of PINCH protein==
==4th LIM domain of PINCH protein==
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<StructureSection load='1nyp' size='340' side='right' caption='[[1nyp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1nyp' size='340' side='right'caption='[[1nyp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1nyp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NYP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1nyp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NYP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1g47|1g47]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LIMS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nyp OCA], [https://pdbe.org/1nyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nyp RCSB], [https://www.ebi.ac.uk/pdbsum/1nyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nyp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nyp OCA], [http://pdbe.org/1nyp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nyp RCSB], [http://www.ebi.ac.uk/pdbsum/1nyp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nyp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LIMS1_HUMAN LIMS1_HUMAN]] Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.
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[https://www.uniprot.org/uniprot/LIMS1_HUMAN LIMS1_HUMAN] Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. Involved in the regulation of cell survival, cell proliferation and cell differentiation.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Qin, J]]
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[[Category: Large Structures]]
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[[Category: Vaynberg, J]]
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[[Category: Qin J]]
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[[Category: Velyvis, A]]
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[[Category: Vaynberg J]]
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[[Category: Vinogradova, O]]
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[[Category: Velyvis A]]
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[[Category: Wu, C]]
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[[Category: Vinogradova O]]
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[[Category: Zhang, Y]]
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[[Category: Wu C]]
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[[Category: Cell adhesion]]
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[[Category: Zhang Y]]
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[[Category: Lim domain]]
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[[Category: Protein recognition]]
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Current revision

4th LIM domain of PINCH protein

PDB ID 1nyp

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