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1ocp

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==SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN==
==SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN==
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<StructureSection load='1ocp' size='340' side='right'caption='[[1ocp]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1ocp' size='340' side='right'caption='[[1ocp]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ocp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ocp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OCP FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">T7 GENE 1 UNDER CONTROL OF THE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocp OCA], [https://pdbe.org/1ocp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocp RCSB], [https://www.ebi.ac.uk/pdbsum/1ocp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ocp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ocp OCA], [https://pdbe.org/1ocp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ocp RCSB], [https://www.ebi.ac.uk/pdbsum/1ocp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ocp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PO5F1_MOUSE PO5F1_MOUSE]] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<ref>PMID:17496161</ref> <ref>PMID:17525163</ref>
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[https://www.uniprot.org/uniprot/PO5F1_MOUSE PO5F1_MOUSE] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<ref>PMID:17496161</ref> <ref>PMID:17525163</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Hayashi, F]]
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[[Category: Hayashi F]]
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[[Category: Kyogoku, Y]]
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[[Category: Kyogoku Y]]
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[[Category: Morita, E H]]
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[[Category: Morita EH]]
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[[Category: Shirakawa, M]]
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[[Category: Shirakawa M]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding protein]]
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Current revision

SOLUTION STRUCTURE OF OCT3 POU-HOMEODOMAIN

PDB ID 1ocp

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