1re6
From Proteopedia
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==Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands== | ==Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands== | ||
| - | <StructureSection load='1re6' size='340' side='right' caption='[[1re6 | + | <StructureSection load='1re6' size='340' side='right'caption='[[1re6]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1re6]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1re6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RE6 FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1re6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1re6 OCA], [https://pdbe.org/1re6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1re6 RCSB], [https://www.ebi.ac.uk/pdbsum/1re6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1re6 ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DYL2_MOUSE DYL2_MOUSE] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/1re6_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/re/1re6_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1re6 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1re6" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Dynein|Dynein]] | + | *[[Dynein 3D structures|Dynein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Barsukov | + | [[Category: Barsukov I]] |
| - | [[Category: Day | + | [[Category: Day CL]] |
| - | [[Category: Hinds | + | [[Category: Hinds MG]] |
| - | [[Category: Huang | + | [[Category: Huang DC]] |
| - | [[Category: Lian | + | [[Category: Lian LY]] |
| - | [[Category: Puthalakath | + | [[Category: Puthalakath H]] |
| - | [[Category: Skea | + | [[Category: Skea G]] |
| - | [[Category: Strasser | + | [[Category: Strasser A]] |
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Current revision
Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands
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Categories: Large Structures | Mus musculus | Barsukov I | Day CL | Hinds MG | Huang DC | Lian LY | Puthalakath H | Skea G | Strasser A
