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1ss6

From Proteopedia

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==Solution structure of SEP domain from human p47==
==Solution structure of SEP domain from human p47==
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<StructureSection load='1ss6' size='340' side='right' caption='[[1ss6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1ss6' size='340' side='right'caption='[[1ss6]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ss6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SS6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ss6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SS6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SS6 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ss6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ss6 OCA], [http://pdbe.org/1ss6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ss6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ss6 PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ss6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ss6 OCA], [https://pdbe.org/1ss6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ss6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ss6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ss6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NSF1C_HUMAN NSF1C_HUMAN]] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).
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[https://www.uniprot.org/uniprot/NSF1C_HUMAN NSF1C_HUMAN] Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP-mediated formation of transitional endoplasmic reticulum (tER) (By similarity). Inhibits the activity of CTSL (in vitro).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ss/1ss6_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ss/1ss6_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Ball, L J]]
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[[Category: Large Structures]]
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[[Category: Buessow, K]]
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[[Category: Ball LJ]]
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[[Category: Labudde, D]]
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[[Category: Buessow K]]
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[[Category: Leidert, M]]
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[[Category: Labudde D]]
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[[Category: Leitner, D]]
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[[Category: Leidert M]]
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[[Category: Oschkinat, H]]
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[[Category: Leitner D]]
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[[Category: Sievert, V]]
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[[Category: Oschkinat H]]
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[[Category: Soukenik, M]]
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[[Category: Sievert V]]
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[[Category: Nmr]]
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[[Category: Soukenik M]]
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[[Category: P47]]
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[[Category: Sep]]
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[[Category: Signaling protein]]
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Current revision

Solution structure of SEP domain from human p47

PDB ID 1ss6

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