This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vlc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:15, 22 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1vlc.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of 3-isopropylmalate dehydrogenase (TM0556) from Thermotoga maritima at 1.90 A resolution==
-
|PDB= 1vlc |SIZE=350|CAPTION= <scene name='initialview01'>1vlc</scene>, resolution 1.90&Aring;
+
<StructureSection load='1vlc' size='340' side='right'caption='[[1vlc]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>
+
<table><tr><td colspan='2'>[[1vlc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VLC FirstGlance]. <br>
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
|GENE= leuB, TM0556 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=PRK00772 PRK00772]</span>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vlc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vlc OCA], [https://pdbe.org/1vlc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vlc RCSB], [https://www.ebi.ac.uk/pdbsum/1vlc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vlc ProSAT], [https://www.topsan.org/Proteins/JCSG/1vlc TOPSAN]</span></td></tr>
-
|RELATEDENTRY=
+
</table>
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vlc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vlc OCA], [http://www.ebi.ac.uk/pdbsum/1vlc PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1vlc RCSB]</span>
+
== Function ==
-
}}
+
[https://www.uniprot.org/uniprot/LEU3_THEMA LEU3_THEMA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vl/1vlc_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vlc ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of 3-isopropylmalate dehydrogenase (TM0556) from Thermotoga maritima at 1.90 A resolution'''
+
==See Also==
-
 
+
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
1VLC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VLC OCA].
+
[[Category: Large Structures]]
-
[[Category: 3-isopropylmalate dehydrogenase]]
+
-
[[Category: Single protein]]
+
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
-
[[Category: JCSG, Joint Center for Structural Genomics.]]
 
-
[[Category: jcsg]]
 
-
[[Category: joint center for structural genomic]]
 
-
[[Category: protein structure initiative]]
 
-
[[Category: psi]]
 
-
[[Category: structural genomic]]
 
-
[[Category: tm0556]]
 
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:25:58 2008''
 

Current revision

Crystal structure of 3-isopropylmalate dehydrogenase (TM0556) from Thermotoga maritima at 1.90 A resolution

PDB ID 1vlc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vlc"
Personal tools