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2keb
From Proteopedia
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==NMR solution structure of the N-terminal domain of the DNA polymerase alpha p68 subunit== | ==NMR solution structure of the N-terminal domain of the DNA polymerase alpha p68 subunit== | ||
| - | <StructureSection load='2keb' size='340' side='right' caption='[[2keb | + | <StructureSection load='2keb' size='340' side='right'caption='[[2keb]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2keb]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2keb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KEB FirstGlance]. <br> |
| - | </td></tr><tr><td class="sblockLbl"><b>[[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2keb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2keb OCA], [https://pdbe.org/2keb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2keb RCSB], [https://www.ebi.ac.uk/pdbsum/2keb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2keb ProSAT]</span></td></tr> |
| - | <table> | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DPOA2_HUMAN DPOA2_HUMAN] May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery (By similarity). | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/2keb_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ke/2keb_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2keb ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2keb" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[DNA polymerase|DNA polymerase]] | + | *[[DNA polymerase 3D structures|DNA polymerase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Chazin | + | [[Category: Large Structures]] |
| - | [[Category: Fanning | + | [[Category: Chazin WJ]] |
| - | [[Category: Fuller | + | [[Category: Fanning E]] |
| - | [[Category: Gao | + | [[Category: Fuller BE]] |
| - | [[Category: Huang | + | [[Category: Gao Y]] |
| - | [[Category: Weiner | + | [[Category: Huang H]] |
| - | [[Category: Wile | + | [[Category: Weiner BE]] |
| - | [[Category: Zhang | + | [[Category: Wile BM]] |
| - | + | [[Category: Zhang H]] | |
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Current revision
NMR solution structure of the N-terminal domain of the DNA polymerase alpha p68 subunit
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Categories: Homo sapiens | Large Structures | Chazin WJ | Fanning E | Fuller BE | Gao Y | Huang H | Weiner BE | Wile BM | Zhang H
