This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7fsy
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7fsy is ON HOLD Authors: Bradshaw, W.J., Katis, V.L., Bountra, C., von Delft, F., Brennan, P.E. Description: SDCBP PanDDA analysis group deposition...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | The | + | ==SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1148165337== |
| + | <StructureSection load='7fsy' size='340' side='right'caption='[[7fsy]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7fsy]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FSY FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=YG5:2-(1H-indazol-1-yl)-N,N-dimethylacetamide'>YG5</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fsy OCA], [https://pdbe.org/7fsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fsy RCSB], [https://www.ebi.ac.uk/pdbsum/7fsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fsy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[3D structures of syntenin|3D structures of syntenin]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| + | [[Category: Bradshaw WJ]] | ||
| + | [[Category: Brennan PE]] | ||
| + | [[Category: Katis VL]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
SDCBP PanDDA analysis group deposition -- The PDZ domans of SDCBP in complex with Z1148165337
| |||||||||||
