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2bn1

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==Insulin after a high dose x-ray burn==
==Insulin after a high dose x-ray burn==
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<StructureSection load='2bn1' size='340' side='right' caption='[[2bn1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='2bn1' size='340' side='right'caption='[[2bn1]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bn1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BN1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BN1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bn1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BN1 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aph|1aph]], [[1bph|1bph]], [[1cph|1cph]], [[1dph|1dph]], [[1ho0|1ho0]], [[1pid|1pid]], [[2bn3|2bn3]], [[2ins|2ins]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bn1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bn1 RCSB], [http://www.ebi.ac.uk/pdbsum/2bn1 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bn1 OCA], [https://pdbe.org/2bn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bn1 RCSB], [https://www.ebi.ac.uk/pdbsum/2bn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bn1 ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/INS_BOVIN INS_BOVIN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bn/2bn1_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bn/2bn1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bn1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2bn1" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]
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*[[Insulin 3D Structures|Insulin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Nanao, M H.]]
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[[Category: Large Structures]]
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[[Category: Ravelli, R B.]]
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[[Category: Nanao MH]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Ravelli RB]]
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[[Category: Glucose metabolism]]
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[[Category: Hormone]]
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[[Category: Insulin family]]
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[[Category: Phasing]]
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[[Category: Radiation damage]]
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[[Category: Rip]]
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Current revision

Insulin after a high dose x-ray burn

PDB ID 2bn1

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