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2c4x

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==STRUCTURAL BASIS FOR THE PROMISCUOUS SPECIFICITY OF THE CARBOHYDRATE-BINDING MODULES FROM THE BETA-SANDWICH SUPER FAMILY==
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<StructureSection load='2c4x' size='340' side='right' caption='[[2c4x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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==Structural basis for the promiscuous specificity of the carbohydrate- binding modules from the beta-sandwich super family==
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<StructureSection load='2c4x' size='340' side='right'caption='[[2c4x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2c4x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C4X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2c4x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C4X FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1wmx|1wmx]], [[1wzx|1wzx]], [[2c24|2c24]], [[2c26|2c26]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4x OCA], [https://pdbe.org/2c4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c4x RCSB], [https://www.ebi.ac.uk/pdbsum/2c4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c4x ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c4x RCSB], [http://www.ebi.ac.uk/pdbsum/2c4x PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/P71140_ACETH P71140_ACETH]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/2c4x_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/2c4x_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c4x ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2c4x" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Glucanase|Glucanase]]
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*[[Glucanase 3D structures|Glucanase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Clostridium thermocellum]]
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[[Category: Acetivibrio thermocellus]]
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[[Category: Alves, V D.]]
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[[Category: Large Structures]]
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[[Category: Bolam, D N.]]
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[[Category: Alves VD]]
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[[Category: Carvalho, A L.]]
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[[Category: Bolam DN]]
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[[Category: Correia, M A.S.]]
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[[Category: Carvalho AL]]
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[[Category: Ferreira, L M.A.]]
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[[Category: Correia MAS]]
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[[Category: Fontes, C M.G A.]]
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[[Category: Ferreira LMA]]
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[[Category: Gilbert, H J.]]
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[[Category: Fontes CMGA]]
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[[Category: Guerreiro, C I.P D.]]
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[[Category: Gilbert HJ]]
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[[Category: Najmudin, S.]]
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[[Category: Guerreiro CIPD]]
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[[Category: Prates, J A.M.]]
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[[Category: Najmudin S]]
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[[Category: Romao, M J.]]
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[[Category: Prates JAM]]
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[[Category: Beta-sandwich protein]]
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[[Category: Romao MJ]]
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[[Category: Carbohydrate binding module]]
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[[Category: Cbm44]]
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[[Category: Cellulase ctcel9d-cel44a]]
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[[Category: Cellulosome]]
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[[Category: Hydrolase]]
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[[Category: Pkd domain]]
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[[Category: Semet derivative]]
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Current revision

Structural basis for the promiscuous specificity of the carbohydrate- binding modules from the beta-sandwich super family

PDB ID 2c4x

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