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2cja

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Current revision (11:26, 22 May 2024) (edit) (undo)
 
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<StructureSection load='2cja' size='340' side='right'caption='[[2cja]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2cja' size='340' side='right'caption='[[2cja]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metbf Metbf]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cja]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._Fusaro Methanosarcina barkeri str. Fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CJA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2cim|2cim]], [[2cj9|2cj9]], [[2cjb|2cjb]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Serine--tRNA_ligase Serine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.11 6.1.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cja OCA], [https://pdbe.org/2cja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cja RCSB], [https://www.ebi.ac.uk/pdbsum/2cja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cja ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cja OCA], [https://pdbe.org/2cja PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cja RCSB], [https://www.ebi.ac.uk/pdbsum/2cja PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cja ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYS2_METBF SYS2_METBF] Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<ref>PMID:15364939</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Metbf]]
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[[Category: Methanosarcina barkeri str. Fusaro]]
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[[Category: Serine--tRNA ligase]]
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[[Category: Ahel D]]
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[[Category: Ahel, D]]
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[[Category: Ban N]]
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[[Category: Ban, N]]
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[[Category: Bilokapic S]]
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[[Category: Bilokapic, S]]
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[[Category: Gruic-Sovulj I]]
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[[Category: Gruic-Sovulj, I]]
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[[Category: Maier T]]
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[[Category: Maier, T]]
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[[Category: Soll D]]
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[[Category: Soll, D]]
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[[Category: Weygand-Durasevic I]]
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[[Category: Weygand-Durasevic, I]]
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[[Category: Ligase]]
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[[Category: Trna synthetase]]
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[[Category: Zinc ion]]
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Current revision

Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with ATP

PDB ID 2cja

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