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2ctz

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[[Image:2ctz.gif|left|200px]]
 
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==Crystal structure of o-acetyl homoserine sulfhydrylase from Thermus thermophilus HB8==
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The line below this paragraph, containing "STRUCTURE_2ctz", creates the "Structure Box" on the page.
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<StructureSection load='2ctz' size='340' side='right'caption='[[2ctz]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ctz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CTZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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{{STRUCTURE_2ctz| PDB=2ctz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ctz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ctz OCA], [https://pdbe.org/2ctz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ctz RCSB], [https://www.ebi.ac.uk/pdbsum/2ctz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ctz ProSAT], [https://www.topsan.org/Proteins/RSGI/2ctz TOPSAN]</span></td></tr>
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</table>
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'''Crystal structure of o-acetyl homoserine sulfhydrylase from Thermus thermophilus HB8'''
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== Function ==
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[https://www.uniprot.org/uniprot/METY1_THET8 METY1_THET8] Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway. Has weak activity with O-acetyl-L-serine, O-phospho-L-serine, L-serine, O-succinyl-L-homoserine and L-homoserine. Shows low CTT beta-lyase activity and very low CTT gamma-synthase activity.<ref>PMID:11566369</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2CTZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CTZ OCA].
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Check<jmol>
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[[Category: Single protein]]
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ct/2ctz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ctz ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Ebihara, A.]]
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[[Category: Ebihara A]]
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[[Category: Imagawa, T.]]
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[[Category: Imagawa T]]
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[[Category: Kousumi, Y.]]
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[[Category: Kousumi Y]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu S]]
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[[Category: Nakagawa, N.]]
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[[Category: Nakagawa N]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Tsuge H]]
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[[Category: Tsuge, H.]]
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[[Category: Utsunomiya H]]
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[[Category: Utsunomiya, H.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Crystal]]
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[[Category: O-acetyl homoserine sulfhydrase]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 23:03:28 2008''
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Current revision

Crystal structure of o-acetyl homoserine sulfhydrylase from Thermus thermophilus HB8

PDB ID 2ctz

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