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2cz0
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="2cz0" size="450" color="white" frame="true" align="right" spinBox="true" caption="2cz0, resolution 1.50Å" /> '''photo-activation sta...) |
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| - | [[Image:2cz0.gif|left|200px]]<br /><applet load="2cz0" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2cz0, resolution 1.50Å" /> | ||
| - | '''photo-activation state of Fe-type NHase in aerobic condition'''<br /> | ||
| - | == | + | ==photo-activation state of Fe-type NHase in aerobic condition== |
| - | + | <StructureSection load='2cz0' size='340' side='right'caption='[[2cz0]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[ | + | <table><tr><td colspan='2'>[[2cz0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ0 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BUA:BUTANOIC+ACID'>BUA</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz0 OCA], [https://pdbe.org/2cz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz0 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz0 TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/NHAA_RHOER NHAA_RHOER] NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class. | |
| - | [ | + | == Evolutionary Conservation == |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | [ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz0_consurf.spt"</scriptWhenChecked> |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | [ | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz0 ConSurf]. | |
| - | [[ | + | <div style="clear:both"></div> |
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| - | [ | + | |
| - | [[ | + | |
| - | [ | + | |
| - | + | ==See Also== | |
| + | *[[Nitrile hydratase|Nitrile hydratase]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rhodococcus erythropolis]] | ||
| + | [[Category: Endo I]] | ||
| + | [[Category: Hashimoto K]] | ||
| + | [[Category: Kamiya N]] | ||
| + | [[Category: Kawano Y]] | ||
| + | [[Category: Nakayama H]] | ||
| + | [[Category: Odaka M]] | ||
| + | [[Category: Takio K]] | ||
Current revision
photo-activation state of Fe-type NHase in aerobic condition
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