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2d3m

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==Pentaketide chromone synthase complexed with coenzyme A==
==Pentaketide chromone synthase complexed with coenzyme A==
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<StructureSection load='2d3m' size='340' side='right' caption='[[2d3m]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='2d3m' size='340' side='right'caption='[[2d3m]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2d3m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aloar Aloar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2D3M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2d3m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aloe_arborescens Aloe arborescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bq6|1bq6]], [[1eeo|1eeo]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3m OCA], [https://pdbe.org/2d3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3m RCSB], [https://www.ebi.ac.uk/pdbsum/2d3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2d3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3m OCA], [http://pdbe.org/2d3m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2d3m RCSB], [http://www.ebi.ac.uk/pdbsum/2d3m PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PCS_ALOAR PCS_ALOAR] Catalyzes the iterative condensations of 5 molecules of malonyl-CoA to produce a pentaketide 5,7-dihydroxy-2-methylchromone.<ref>PMID:15686354</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3m_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3m_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aloar]]
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[[Category: Aloe arborescens]]
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[[Category: Abe, I]]
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[[Category: Large Structures]]
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[[Category: Kohno, T]]
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[[Category: Abe I]]
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[[Category: Kondo, S]]
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[[Category: Kohno T]]
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[[Category: Morita, H]]
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[[Category: Kondo S]]
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[[Category: Noguchi, H]]
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[[Category: Morita H]]
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[[Category: Oguro, S]]
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[[Category: Noguchi H]]
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[[Category: Sugio, S]]
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[[Category: Oguro S]]
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[[Category: Chalcone synthase]]
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[[Category: Sugio S]]
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[[Category: Pentaketide chromone synthase]]
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[[Category: Polyketide synthase]]
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[[Category: Transferase]]
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Current revision

Pentaketide chromone synthase complexed with coenzyme A

PDB ID 2d3m

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