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8ykv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of succinate receptor SUCR1 bound to compound 31== | |
| - | + | <StructureSection load='8ykv' size='340' side='right'caption='[[8ykv]], [[Resolution|resolution]] 2.48Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ykv]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8YKV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8YKV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.48Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1LYV:(2~{S})-2-[[6-[4-(trifluoromethyloxy)phenyl]pyridin-2-yl]carbonylamino]butanedioic+acid'>A1LYV</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ykv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ykv OCA], [https://pdbe.org/8ykv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ykv RCSB], [https://www.ebi.ac.uk/pdbsum/8ykv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ykv ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref> |
| - | [[Category: Fu | + | == References == |
| - | [[Category: Liu | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Fu W]] | ||
| + | [[Category: Li C]] | ||
| + | [[Category: Li J]] | ||
| + | [[Category: Liu H]] | ||
| + | [[Category: Xu HE]] | ||
| + | [[Category: Zhu H]] | ||
Current revision
Cryo-EM structure of succinate receptor SUCR1 bound to compound 31
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Categories: Bos taurus | Homo sapiens | Large Structures | Rattus norvegicus | Synthetic construct | Fu W | Li C | Li J | Liu H | Xu HE | Zhu H
