This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8z90
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2== | |
| - | + | <StructureSection load='8z90' size='340' side='right'caption='[[8z90]], [[Resolution|resolution]] 2.87Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8z90]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thogoto_virus_(isolate_SiAr_126) Thogoto virus (isolate SiAr 126)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z90 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.87Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2P:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>G2P</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z90 OCA], [https://pdbe.org/8z90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z90 RCSB], [https://www.ebi.ac.uk/pdbsum/8z90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z90 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PA_THOGV PA_THOGV] Initiates transcription by a unique cap-stealing mechanism that involves the cleavage of only the m(7)GpppAm structure from cellular hnRNAs. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chang T]] | ||
| + | [[Category: Chen X]] | ||
| + | [[Category: Xiong X]] | ||
| + | [[Category: Xue L]] | ||
Current revision
Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2
| |||||||||||
Categories: Large Structures | Chang T | Chen X | Xiong X | Xue L
